Chemical Body Burden refers to the measurement or load of chemicals in the body. This load can be detected through blood, urine, breastmilk sampling or any number of biomonitoring activities. Chemicals in the body could have numerous harmful effects and could weaken the immune system, making the body more susceptible to disease. The burden may be due to bioaccumulation through various mechanisms of exposure. Understanding the amount and types of chemicals in the body can help us know what chemicals are mobile in the environment. Chemical Body Burden is important to sustainability because it can make known the chemicals with the greatest bioaccumulation in nature and greatest exposures to humans, helping to inform future design of chemicals and products that avoid these unintentional impacts.